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Orlistat

Orlistat is a reversible inhibitor of lipases. It exerts its therapeutic activity non-systemically in the lumen of the stomach and small intestine by forming a covalent bond with the active serine site of gastric and pancreatic lipases. Unlike other obesity drugs, orlistat prevents enzymes in the gastrointestinal tract from breaking down dietary fats into smaller molecules that can be absorbed by the body. Absorption of fat is decreased by about 30 percent.

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Side effects

The following side effects occur commonly with the use of orlistat.
*oily or fatty stools;
*orange or brown colored oil in your stool;
*gas with discharge
*loose stools, or an urgent need to go to the bathroom
*stomach pain, nausea, vomiting
Other side effects that may occur while taking orlistat include:
*cold or flu symptoms
*headache, back pain
*skin rash or itching

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Xenical

Xenical is a weight control medication that has been approve by the United States Federal Drug Administration, as well as, been extensively tested throughout Europe. Distinct from other medicines that stimulate the brain to suppress appetite, Xenical uses a fat blocking mode of action that works non-systematically in the gastrointestinal tract. The end result is approximately 30 percent of dietary fat passes through the body undigested. Therefore, Xenical blocks some 30% of the calories from fat from being absorbed.

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History

Since it's approval by the FDA, Xenical has become the fastest-selling diet medication on the market today — and for good reason. Years of clinical testing have demonstrated that it is effective. People dieting with Xenical lost an average of 50 percent more weight than those dieting without it. .

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Obesity

The definition of obesity varies depending on what one reads, but in general, it is a chronic condition defined by an excess amount body fat. A certain amount of body fat is necessary for storing energy, heat insulation, shock absorption, and other functions. The normal amount of body fat (expressed as percentage of body fat) is between 25-30% in women and 18-23% in men. Women with over 30% body fat and men with over 25% body fat are considered obese.

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Leaflet

Read all of this leaflet carefully before you start taking this medicine
* If you have any further questions, please ask your doctor or your pharmacist.
* This medicine has been prescribed for you. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
* If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.

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